HTLV-1 clonality during chronic infection and BLV clonality during primary infection
نویسندگان
چکیده
منابع مشابه
HTLV-1 clonality in adult T-cell leukaemia and non-malignant HTLV-1 infection
Human T lymphotropic virus type 1 (HTLV-1) causes a range of chronic inflammatory diseases and an aggressive malignancy of T lymphocytes known as adult T-cell leukaemia/lymphoma (ATLL). A cardinal feature of HTLV-1 infection is the presence of expanded clones of HTLV-1-infected T cells, which may persist for decades. A high viral burden (proviral load) is associated with both the inflammatory a...
متن کاملQuantification of HTLV-1 Clonality and TCR Diversity
Estimation of immunological and microbiological diversity is vital to our understanding of infection and the immune response. For instance, what is the diversity of the T cell repertoire? These questions are partially addressed by high-throughput sequencing techniques that enable identification of immunological and microbiological "species" in a sample. Estimators of the number of unseen specie...
متن کاملSeroepidemiology of HTLV-1 and HTLV-2 Infection in Neyshabur City, North-Eastern Iran, during 2010-2014
Background: Retroviruses of human T-lymphotropic viruses (HTLV-1 and HTLV-2) have been demonstrated to be endemic in the north-eastern region of Iran. This study aims to determine HTLV-1 and HTLV-2 prevalence among healthy individuals in Neyshabur City during 2010-2014. Methods: A total of 8054 blood samples were collected from healthy participants in Neyshabur, North-Eastern Iran. The blood sa...
متن کاملClonality of chronic neutrophilic leukemia.
Kwong and Cheng’ recently reported a case of chronic neutrophilic leukemia (CNL) with absence of Philadelphia (Ph) chromosome and no bcr rearrangement. They showed the clonal nature of CNL by the methylation status of the X-linked hypoxanthine phosphoribosyl transferase. (HPRT) gene. The clonal myeloproliferative nature of CNL was first documented in our report of a case of polycythemia vera (P...
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ژورنال
عنوان ژورنال: Retrovirology
سال: 2011
ISSN: 1742-4690
DOI: 10.1186/1742-4690-8-s1-a185